Radioprotective Effect of Sodium Hydrogen S-(2-L-Pyrrolidyl-methyl) phosphorothioate in Mice
نویسندگان
چکیده
منابع مشابه
Radioprotective effect of hydrogen in cultured cells and mice.
It has been demonstrated that hydrogen can selectively reduce hydroxyl and peroxynitrite in vitro. Since most of the ionizing radiation-induced cellular damage is caused by hydroxyl radicals, this study was designed to test the hypothesis that hydrogen may be an effective radioprotective agent. This paper demonstrates that treating cells with hydrogen before irradiation could significantly inhi...
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Molecular beacons (MBs) have shown great potential for the imaging of RNAs within single living cells; however, the ability to perform accurate measurements of RNA expression can be hampered by false-positives resulting from nonspecific interactions and/or nuclease degradation. These false-positives could potentially be avoided by introducing chemically modified oligonucleotides into the MB des...
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Radioprotective agents like selenium are used to reduce the damage caused by radiation in healthy tissues. The aim of this study was to evaluate the effect of sodium selenite on the development of the molars of offspring of rats irradiated during odontogenesis. Twenty pregnant rats were randomly divided into 4 groups: control, irradiated, selenium and selenium/irradiated. The selenium and selen...
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Background: Medical use of ionizing radiation has direct/indirect undesirable effects on normal tissues. In this study, the radioprotective effect of arbutin in megavoltage therapeutic x-irradiated mice was investigated using serum alkaline phosphatase (ALP), alanine aminotransferase (ALT), and asparate amniotransferase (AST) activity measurements. Material and Methods: In this analytical...
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The administration of 5-azacytidine to mice (AKR strain) prior to irradiation with a supralethal dose of X-rays markedly reduces their mortality. In the pretreated animals the number of blood leukocytes and of bone marrow nucleated cells is considerably higher than in the animals that have been only irradiated. It is supposed that the radioprotective effect of 5-azacytidine favourably in fluen...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1973
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.21.2722